The FHR was assessed daily by Doppler and remained within normal limits. Obstetric ultrasound examination showed no fetal anomalies, normal amniotic fluid volume with fetal body movements, and an estimated fetal weight of 381 g (−0.9 SD). Blood test results and chest radiography were normal. She was diagnosed with COVID-19 and referred to our hospital at 21 weeks and 4 days (day 0).Īt the time of admission, she was asymptomatic, with a body temperature of 37.1☌, pulse rate of 75 bpm, blood pressure of 94/66 mmHg, respiratory rate of 18 bpm, and SpO2 of 98% on room air. SARS-CoV-2 reverse-transcription polymerase chain reaction (RT-PCR) was performed using a nasopharyngeal swab at 21 weeks and 3 days of gestational age since she had close contact with her COVID-19-positive husband. We report a case of a 22-year-old gravida 2, para 1 Japanese woman, whose pregnancy course was uncomplicated with no relevant medical history, and her body mass index was 19 kg/m 2. Herein, we present a case of intrauterine fetal death characterized by typical hypoxic changes in the FHR and coagulopathy in the second trimester of a COVID-19 pregnancy, presumed to be caused by placental insufficiency due to SARS-CoV-2 placentitis. 3 Furthermore, a paucity of reports discuss changes in fetal heart rate (FHR) monitoring during COVID-19 pregnancy and its association with SARS-CoV-2 infection. 1, 2 However, the potential effects on fetal and neonatal outcomes are poorly understood, and vertical transmission to the fetus remains debated. Accumulated data describe adverse perinatal outcomes, such as premature rupture of membranes, preterm labor, intrauterine growth restriction, intrauterine fetal distress and death, and neonatal death. Poor hare! Tired and in disgrace, he slumped down beside the tortoise who was silently smiling at him.Since the novel coronavirus disease 2019 (COVID-19) pandemic, various effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on both mother and fetus have emerged. But the hare’s last leap was just too late, for the tortoise had beaten him to the winning post. Just a little more and he’d be first at the finish. He leapt and bounded at a great rate, his tongue lolling, and gasping for breath. He could see the tortoise a speck in the distance and away he dashed. At that very point, the hare woke with a jolt. The sun started to sink, below the horizon, and the tortoise, who had been plodding towards the winning post since morning, was scarcely a yard from the finish. And smiling at the thought of the look on the tortoise’s face when it saw the hare speed by, he fell fast asleep and was soon snoring happily. With a careless glance at the tortoise, now halfway along the course, he decided to have another snooze before flashing past the winning post. But the heavy meal and the hot sun made his eyelids droop. Breathing a sigh of relief, the hare decided he might as well have breakfast too, and off he went to munch some cabbages he had noticed in a nearby field. But the creature was only a short distance away, having barely covered a third of the course. The hare woke with a start from a fitful sleep and gazed round, looking for the tortoise. “I’ll have forty winks and catch up with you in a minute.” When the hare saw how painfully slow his rival was, he decided, half asleep on his feet, to have a quick nap. The hare yawned sleepily as the meek tortoise trudged slowly off. A course was planned, and the next day at dawn they stood at the starting line. Now, why don’t you try?”Īnnoyed by such bragging, the tortoise accepted the challenge. “Beaten in a race? By whom? Not you, surely! I bet there’s nobody in the world that can win against me, I’m so speedy. Then one day, the irate tortoise answered back: “Who do you think you are? There’s no denying you’re swift, but even you can be beaten!” The hare squealed with laughter. Once upon a time there was a hare who, boasting how he could run faster than anyone else, was forever teasing tortoise for its slowness.
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